Dr. Elizabeth Lippard received a ROI from the National Institute on Alcohol Abuse and Alcoholism for her research proposal entitled "Dissecting Responses to Alcohol in Individuals with Familial Risk for Bipolar Disorder". Bipolar disorder has the highest rate of alcohol use disorder of any psychiatric diagnosis, yet our understanding of mechanisms that contribute to this comorbidity is limited. This research project will investigate if familial risk for bipolar disorder and/or alcohol use disorder is associated with altered sensitivity to alcohol and risky alcohol use patterns. The findings could possibly suggest novel biomarkers capable of predicting risk and identifying targets for early intervention, treatment, and education strategies to improve public health.